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Hic-5 Controls BMP4 Responses in Prostate Cancer Cells through Interacting with Smads 1, 5 and 8

Hydrogen peroxide-inducible clone-5 (Hic-5, or androgen receptor-associated protein 55) is a transforming growth factor-β (TGF-β)-inducible LIM protein whose deregulation is implicated in the progression of prostate cancer. Here we report that Hic-5 binds to Smads 1, 5 and 8, and represses bone morp...

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Detalles Bibliográficos
Autores principales: Shola, Dorjee T.N., Wang, Hui, Wahdan-Alaswad, Reema, Danielpour, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340512/
https://www.ncbi.nlm.nih.gov/pubmed/21996749
http://dx.doi.org/10.1038/onc.2011.422