Cargando…
Hic-5 Controls BMP4 Responses in Prostate Cancer Cells through Interacting with Smads 1, 5 and 8
Hydrogen peroxide-inducible clone-5 (Hic-5, or androgen receptor-associated protein 55) is a transforming growth factor-β (TGF-β)-inducible LIM protein whose deregulation is implicated in the progression of prostate cancer. Here we report that Hic-5 binds to Smads 1, 5 and 8, and represses bone morp...
Autores principales: | Shola, Dorjee T.N., Wang, Hui, Wahdan-Alaswad, Reema, Danielpour, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340512/ https://www.ncbi.nlm.nih.gov/pubmed/21996749 http://dx.doi.org/10.1038/onc.2011.422 |
Ejemplares similares
-
Critical Role of a Survivin/TGF-β/mTORC1 Axis in IGF-I-Mediated Growth of Prostate Epithelial Cells
por: Song, Kyung, et al.
Publicado: (2013) -
Jagged-1 is induced by mTOR inhibitors in renal cancer cells through an Akt/ALK5/Smad4-dependent mechanism
por: Danielpour, David, et al.
Publicado: (2022) -
BMP-7 suppresses excessive scar formation by activating the BMP-7/Smad1/5/8 signaling pathway
por: Guo, Jingdong, et al.
Publicado: (2017) -
BMP4 Enhances Foam Cell Formation by BMPR-2/Smad1/5/8 Signaling
por: Feng, Jun, et al.
Publicado: (2014) -
Wedelolactone Enhances Osteoblastogenesis through ERK- and JNK-mediated BMP2 Expression and Smad/1/5/8 Phosphorylation
por: Zhu, Di, et al.
Publicado: (2018)