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Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells

The primary cilium is an antenna-like organelle that modulates differentiation, sensory functions, and signal transduction. After cilia are disassembled at the G0/G1 transition, formation of cilia is strictly inhibited in proliferating cells. However, the mechanisms of this inhibition are unknown. I...

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Detalles Bibliográficos
Autores principales: Inoko, Akihito, Matsuyama, Makoto, Goto, Hidemasa, Ohmuro-Matsuyama, Yuki, Hayashi, Yuko, Enomoto, Masato, Ibi, Miho, Urano, Takeshi, Yonemura, Shigenobu, Kiyono, Tohru, Izawa, Ichiro, Inagaki, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341160/
https://www.ncbi.nlm.nih.gov/pubmed/22529102
http://dx.doi.org/10.1083/jcb.201106101