ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting

The sorting of signaling receptors to lysosomes is an essential regulatory process in mammalian cells. During degradation, receptors are modified with ubiquitin and sorted by endosomal sorting complex required for transport (ESCRT)–0, –I, –II, and –III complexes into intraluminal vesicles (ILVs) of...

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Detalles Bibliográficos
Autores principales: Dores, Michael R., Chen, Buxin, Lin, Huilan, Soh, Unice J.K., Paing, May M., Montagne, William A., Meerloo, Timo, Trejo, JoAnn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341166/
https://www.ncbi.nlm.nih.gov/pubmed/22547407
http://dx.doi.org/10.1083/jcb.201110031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341166/
https://www.ncbi.nlm.nih.gov/pubmed/22547407
http://dx.doi.org/10.1083/jcb.201110031

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