Mifepristone Increases the Cytotoxicity of Uterine Natural Killer Cells by Acting as a Glucocorticoid Antagonist via ERK Activation

BACKGROUND: Mifepristone (RU486), a potent antagonist of progesterone and glucocorticoids, is involved in immune regulation. Our previous studies demonstrated that mifepristone directly augments the cytotoxicity of human uterine natural killer (uNK) cells. However, the mechanism responsible for this...

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Detalles Bibliográficos
Autores principales: Chen, Yuezhou, Wang, Yan, Zhuang, Yaling, Zhou, Feng, Huang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341349/
https://www.ncbi.nlm.nih.gov/pubmed/22563497
http://dx.doi.org/10.1371/journal.pone.0036413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341349/
https://www.ncbi.nlm.nih.gov/pubmed/22563497
http://dx.doi.org/10.1371/journal.pone.0036413

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