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Human Gastric Mucins Differently Regulate Helicobacter pylori Proliferation, Gene Expression and Interactions with Host Cells

Helicobacter pylori colonizes the mucus niche of the gastric mucosa and is a risk factor for gastritis, ulcers and cancer. The main components of the mucus layer are heavily glycosylated mucins, to which H. pylori can adhere. Mucin glycosylation differs between individuals and changes during disease...

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Detalles Bibliográficos
Autores principales: Skoog, Emma C., Sjöling, Åsa, Navabi, Nazanin, Holgersson, Jan, Lundin, Samuel B., Lindén, Sara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341350/
https://www.ncbi.nlm.nih.gov/pubmed/22563496
http://dx.doi.org/10.1371/journal.pone.0036378