Antiproliferative Effects of DNA Methyltransferase 3B Depletion Are Not Associated with DNA Demethylation

Silencing of genes by hypermethylation contributes to cancer progression and has been shown to occur with increased frequency at specific genomic loci. However, the precise mechanisms underlying the establishment and maintenance of aberrant methylation marks are still elusive. The de novo DNA methyl...

Descripción completa

Detalles Bibliográficos
Autores principales: Hagemann, Sabine, Kuck, Dirk, Stresemann, Carlo, Prinz, Florian, Brueckner, Bodo, Mund, Cora, Mumberg, Dominik, Sommer, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341356/
https://www.ncbi.nlm.nih.gov/pubmed/22563479
http://dx.doi.org/10.1371/journal.pone.0036125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341356/
https://www.ncbi.nlm.nih.gov/pubmed/22563479
http://dx.doi.org/10.1371/journal.pone.0036125

Ejemplares similares