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Functional Evidence of Multidrug Resistance Transporters (MDR) in Rodent Olfactory Epithelium

BACKGROUND: P-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP1) are membrane transporter proteins which function as efflux pumps at cell membranes and are considered to exert a protective function against the entry of xenobiotics. While evidence for Pgp and MRP transporter activi...

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Detalles Bibliográficos
Autores principales: Molinas, Adrien, Sicard, Gilles, Jakob, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341370/
https://www.ncbi.nlm.nih.gov/pubmed/22563480
http://dx.doi.org/10.1371/journal.pone.0036167