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Palmitate Activates Autophagy in INS-1E β-Cells and in Isolated Rat and Human Pancreatic Islets

We have investigated the in vitro effects of increased levels of glucose and free fatty acids on autophagy activation in pancreatic beta cells. INS-1E cells and isolated rat and human pancreatic islets were incubated for various times (from 2 to 24 h) at different concentrations of glucose and/or pa...

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Detalles Bibliográficos
Autores principales: Martino, Luisa, Masini, Matilde, Novelli, Michela, Beffy, Pascale, Bugliani, Marco, Marselli, Lorella, Masiello, Pellegrino, Marchetti, Piero, De Tata, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341371/
https://www.ncbi.nlm.nih.gov/pubmed/22563482
http://dx.doi.org/10.1371/journal.pone.0036188