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Pancreatic Transcription Factors Containing Protein Transduction Domains Drive Mouse Embryonic Stem Cells towards Endocrine Pancreas

Protein transduction domains (PTDs), such as the HIV1-TAT peptide, have been previously used to promote the uptake of proteins into a range of cell types, including stem cells. Here we generated pancreatic transcription factors containing PTD sequences and administered these to endoderm enriched mou...

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Detalles Bibliográficos
Autores principales: Lima, Maria João, Docherty, Hilary M., Chen, Yuanxiao, Vallier, Ludovic, Docherty, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341374/
https://www.ncbi.nlm.nih.gov/pubmed/22563503
http://dx.doi.org/10.1371/journal.pone.0036481