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Intermedin Stabilized Endothelial Barrier Function and Attenuated Ventilator-induced Lung Injury in Mice

BACKGROUND: Even protective ventilation may aggravate or induce lung failure, particularly in preinjured lungs. Thus, new adjuvant pharmacologic strategies are needed to minimize ventilator-induced lung injury (VILI). Intermedin/Adrenomedullin-2 (IMD) stabilized pulmonary endothelial barrier functio...

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Detalles Bibliográficos
Autores principales: Müller-Redetzky, Holger Christian, Kummer, Wolfgang, Pfeil, Uwe, Hellwig, Katharina, Will, Daniel, Paddenberg, Renate, Tabeling, Christoph, Hippenstiel, Stefan, Suttorp, Norbert, Witzenrath, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341380/
https://www.ncbi.nlm.nih.gov/pubmed/22563471
http://dx.doi.org/10.1371/journal.pone.0035832