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ZIP8 Zinc Transporter: Indispensable Role for Both Multiple-Organ Organogenesis and Hematopoiesis In Utero
Previously this laboratory characterized Slc39a8-encoded ZIP8 as a Zn(2+)/(HCO(3) (–))(2) symporter; yet, the overall physiological importance of ZIP8 at the whole-organism level remains unclear. Herein we describe the phenotype of the hypomorphic Slc39a8(neo/neo) mouse which has retained the neomyc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341399/ https://www.ncbi.nlm.nih.gov/pubmed/22563477 http://dx.doi.org/10.1371/journal.pone.0036055 |