Down-regulation of flavin reductase and alcohol dehydrogenase-1 (ADH1) in metronidazole-resistant isolates of Trichomonas vaginalis

The microaerophilic parasite Trichomonas vaginalis is a causative agent of painful vaginitis or urethritis, termed trichomoniasis, and can also cause preterm delivery or stillbirth. Treatment of trichomoniasis is almost exclusively based on the nitroimidazole drugs metronidazole and tinidazole. Metr...

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Detalles Bibliográficos
Autores principales: Leitsch, David, Drinić, Mirjana, Kolarich, Daniel, Duchêne, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341570/
https://www.ncbi.nlm.nih.gov/pubmed/22449940
http://dx.doi.org/10.1016/j.molbiopara.2012.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341570/
https://www.ncbi.nlm.nih.gov/pubmed/22449940
http://dx.doi.org/10.1016/j.molbiopara.2012.03.003

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