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Elevated levels of the steroidogenic factor 1 are associated with over-expression of CYP19 in an oestrogen-producing testicular Leydig cell tumour

BACKGROUND AND OBJECTIVES: Testicular Leydig cell tumours (LCTs) are rare, steroid-secreting tumours. Elevated levels of aromatase (CYP19 or CYP19A1) mRNA have been previously described in LCTs; however, little is known about the mechanism(s) causing CYP19 over-expression. We report an LCT in a 29-y...

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Detalles Bibliográficos
Autores principales: Straume, Anne Hege, Løvås, Kristian, Miletic, Hrvoje, Gravdal, Karsten, Lønning, Per Eystein, Knappskog, Stian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioScientifica 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341656/
https://www.ncbi.nlm.nih.gov/pubmed/22301800
http://dx.doi.org/10.1530/EJE-11-0849