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ApoA-1 mimetic restores adiponectin expression and insulin sensitivity independent of changes in body weight in female obese mice

BACKGROUND: We examined the ability of the apolipoprotein AI mimetic peptide L-4F to improve the metabolic state of female and male ob mice and the mechanisms involved. METHODS: Female and male lean and obese (ob) mice were administered L-4F or vehicle for 6 weeks. Body weight was measured weekly. F...

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Detalles Bibliográficos
Autores principales: Marino, J S, Peterson, S J, Li, M, Vanella, L, Sodhi, K, Hill, J W, Abraham, N G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341710/
https://www.ncbi.nlm.nih.gov/pubmed/23169576
http://dx.doi.org/10.1038/nutd.2012.4