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Apoptosome-dependent caspase activation proteins as prognostic markers in Stage II and III colorectal cancer
BACKGROUND: Critical to successful execution of mitochondrial-mediated apoptosis is apoptosome formation and subsequent activation of caspases. Defects in this pathway have an important role in colorectal carcinogenesis and chemoresistance; therefore, the expression of apoptosome-associated proteins...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341858/ https://www.ncbi.nlm.nih.gov/pubmed/22481083 http://dx.doi.org/10.1038/bjc.2012.133 |