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The Relationship between CD27 Negative and Positive B Cell Populations in Human Peripheral Blood

CD27 expression has been used to distinguish between memory and naive B cells in humans. However, low levels of mutated and isotype-switched CD27−IgD− cells are seen in healthy adults, and these are increased in some autoimmune diseases and in the elderly. Thus CD27 is not a universal marker of memo...

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Detalles Bibliográficos
Autores principales: Wu, Yu-Chang Bryan, Kipling, David, Dunn-Walters, Deborah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341955/
https://www.ncbi.nlm.nih.gov/pubmed/22566870
http://dx.doi.org/10.3389/fimmu.2011.00081