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The Relationship between CD27 Negative and Positive B Cell Populations in Human Peripheral Blood
CD27 expression has been used to distinguish between memory and naive B cells in humans. However, low levels of mutated and isotype-switched CD27−IgD− cells are seen in healthy adults, and these are increased in some autoimmune diseases and in the elderly. Thus CD27 is not a universal marker of memo...
Autores principales: | Wu, Yu-Chang Bryan, Kipling, David, Dunn-Walters, Deborah K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341955/ https://www.ncbi.nlm.nih.gov/pubmed/22566870 http://dx.doi.org/10.3389/fimmu.2011.00081 |
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