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Pathogenic CD8 T Cells in Multiple Sclerosis and Its Experimental Models

A growing body of evidence suggests that autoreactive CD8 T cells contribute to the disease process in multiple sclerosis (MS). Lymphocytes in MS plaques are biased toward the CD8 lineage, and MS patients harbor CD8 T cells specific for multiple central nervous system (CNS) antigens. Currently, ther...

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Detalles Bibliográficos
Autores principales: Huseby, Eric S., Huseby, Priya G., Shah, Shivanee, Smith, Rebecca, Stadinski, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341980/
https://www.ncbi.nlm.nih.gov/pubmed/22566945
http://dx.doi.org/10.3389/fimmu.2012.00064