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A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

The prevalence of obesity and type 2-diabetes is increasing worldwide and threatens to shorten lifespan. Impaired insulin action in peripheral tissues is a major pathogenic factor. Insulin stimulates glucose uptake in adipose tissue through the Glut4-glucose transporter and alterations in adipose-Gl...

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Detalles Bibliográficos
Autores principales: Herman, Mark A., Peroni, Odile D., Villoria, Jorge, Schön, Michael R., Abumrad, Nada A., Blüher, Matthias, Klein, Samuel, Kahn, Barbara B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341994/
https://www.ncbi.nlm.nih.gov/pubmed/22466288
http://dx.doi.org/10.1038/nature10986