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Humoral Alloimmunity in Transplantation: Relevance of HLA Epitope Antigenicity and Immunogenicity
HLA mismatching is an important risk factor for antibody-mediated rejection and transplant failure. With the realization HLA antibodies recognize epitopes rather than antigens, it has become apparent that donor-recipient compatibility should be assessed at the epitope level. Recent developments have...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342002/ https://www.ncbi.nlm.nih.gov/pubmed/22566848 http://dx.doi.org/10.3389/fimmu.2011.00059 |