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Antigen Cross-Priming of Cell-Associated Proteins is Enhanced by Macroautophagy within the Antigen Donor Cell

Phagocytosis of dying cells constitutes an important mechanism of antigen capture for the cross-priming of CD8(+) T cells. This process has been shown to be critical for achieving tumor and viral immunity. While most studies have focused on the mechanisms inherent in the dendritic cell that account...

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Detalles Bibliográficos
Autores principales: Joubert, Pierre-Emmanuel, Albert, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342049/
https://www.ncbi.nlm.nih.gov/pubmed/22566942
http://dx.doi.org/10.3389/fimmu.2012.00061