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Computational models for in-vitro anti-tubercular activity of molecules based on high-throughput chemical biology screening datasets

BACKGROUND: The emergence of Multi-drug resistant tuberculosis in pandemic proportions throughout the world and the paucity of novel therapeutics for tuberculosis have re-iterated the need to accelerate the discovery of novel molecules with anti-tubercular activity. Though high-throughput screens fo...

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Detalles Bibliográficos
Autores principales: Periwal, Vinita, Kishtapuram, Shireesha, Scaria, Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342097/
https://www.ncbi.nlm.nih.gov/pubmed/22463123
http://dx.doi.org/10.1186/1471-2210-12-1