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Inhibition of HIV-1 replication with stable RNAi-mediated knockdown of autophagy factors
Autophagy is a cellular process leading to the degradation of cytoplasmic components such as organelles and intracellular pathogens. It has been shown that HIV-1 relies on several components of the autophagy pathway for its replication, but the virus also blocks late steps of autophagy to prevent it...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342116/ https://www.ncbi.nlm.nih.gov/pubmed/22424437 http://dx.doi.org/10.1186/1743-422X-9-69 |