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EGF activates TTP expression by activation of ELK-1 and EGR-1 transcription factors

BACKGROUND: Tristetraprolin (TTP) is a key mediator of processes such as inflammation resolution, the inhibition of autoimmunity and in cancer. It carries out this role by the binding and degradation of mRNA transcripts, thereby decreasing their half-life. Transcripts modulated by TTP encode protein...

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Detalles Bibliográficos
Autores principales: Florkowska, Magdalena, Tymoszuk, Piotr, Balwierz, Aleksandra, Skucha, Anna, Kochan, Jakub, Wawro, Mateusz, Stalinska, Krystyna, Kasza, Aneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342124/
https://www.ncbi.nlm.nih.gov/pubmed/22433566
http://dx.doi.org/10.1186/1471-2199-13-8