In vivo efficacy of the histone deacetylase inhibitor suberoylanilide hydroxamic acid in combination with radiotherapy in a malignant rhabdoid tumor mouse model

PURPOSE: Histone deacetylase inhibitors are promising new substances in cancer therapy and have also been shown to sensitize different tumor cells to irradiation (XRT). We explored the effect as well as the radiosensitizing properties of suberoylanilide hydroxamic acid (SAHA) in vivo in a malignant...

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Detalles Bibliográficos
Autores principales: Thiemann, Markus, Oertel, Susanne, Ehemann, Volker, Weichert, Wilko, Stenzinger, Albrecht, Bischof, Marc, Weber, Klaus-J, Perez, Ramon Lopez, Haberkorn, Uwe, Kulozik, Andreas E, Debus, Jürgen, Huber, Peter E, Battmann, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342162/
https://www.ncbi.nlm.nih.gov/pubmed/22458853
http://dx.doi.org/10.1186/1748-717X-7-52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342162/
https://www.ncbi.nlm.nih.gov/pubmed/22458853
http://dx.doi.org/10.1186/1748-717X-7-52

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