Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts

BACKGROUND: Small airway narrowing is an important pathology which impacts lung function in chronic obstructive pulmonary disease (COPD). The accumulation of fibroblasts and myofibroblasts contribute to inflammation, remodeling and fibrosis by production and release of mediators such as cytokines, p...

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Detalles Bibliográficos
Autores principales: Tannheimer, Stacey L, Wright, Clifford D, Salmon, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342220/
https://www.ncbi.nlm.nih.gov/pubmed/22452977
http://dx.doi.org/10.1186/1465-9921-13-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342220/
https://www.ncbi.nlm.nih.gov/pubmed/22452977
http://dx.doi.org/10.1186/1465-9921-13-28

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