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P3 mAb: An Immunogenic Anti-NeuGcGM3 Antibody with Unusual Immunoregulatory Properties

P3 is a murine IgM mAb that recognize N-glycosylated gangliosides, sulfatides, and antigens expressed in melanoma, breast, and lung human tumors. This antibody has the ability to trigger an IgG antibody response in the syngeneic BALB/c model, even when it is administered in the absence of adjuvant o...

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Detalles Bibliográficos
Autores principales: Martínez, Darel, Rodríguez, Nely, Griñán, Tania, Rondón, Teresa, Vázquez, Ana María, Pérez, Rolando, Hernández, Ana María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342266/
https://www.ncbi.nlm.nih.gov/pubmed/22566972
http://dx.doi.org/10.3389/fimmu.2012.00094