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Transcriptional Enhancers in Protein-Coding Exons of Vertebrate Developmental Genes

Many conserved noncoding sequences function as transcriptional enhancers that regulate gene expression. Here, we report that protein-coding DNA also frequently contains enhancers functioning at the transcriptional level. We tested the enhancer activity of 31 protein-coding exons, which we chose base...

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Detalles Bibliográficos
Autores principales: Ritter, Deborah I., Dong, Zhiqiang, Guo, Su, Chuang, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342275/
https://www.ncbi.nlm.nih.gov/pubmed/22567096
http://dx.doi.org/10.1371/journal.pone.0035202