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The Intracellular Virus-Containing Compartments in Primary Human Macrophages Are Largely Inaccessible to Antibodies and Small Molecules

HIV-1 assembly and release occurs at the plasma membrane of human T lymphocytes and model epithelial cell lines, whereas in macrophages intracellular sites of virus assembly or accumulation predominate. The origin of the intracellular virus-containing compartment (VCC) has been controversial. This c...

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Detalles Bibliográficos
Autores principales: Chu, Hin, Wang, Jaang-Jiun, Qi, Mingli, Yoon, Jeong-Joong, Wen, Xiaoyun, Chen, Xuemin, Ding, Lingmei, Spearman, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342280/
https://www.ncbi.nlm.nih.gov/pubmed/22567100
http://dx.doi.org/10.1371/journal.pone.0035297