Altered Composition of Liver Proteasome Assemblies Contributes to Enhanced Proteasome Activity in the Exceptionally Long-Lived Naked Mole-Rat

The longest-lived rodent, the naked mole-rat (Bathyergidae; Heterocephalus glaber), maintains robust health for at least 75% of its 32 year lifespan, suggesting that the decline in genomic integrity or protein homeostasis routinely observed during aging, is either attenuated or delayed in this extra...

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Detalles Bibliográficos
Autores principales: Rodriguez, Karl A., Edrey, Yael H., Osmulski, Pawel, Gaczynska, Maria, Buffenstein, Rochelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342291/
https://www.ncbi.nlm.nih.gov/pubmed/22567116
http://dx.doi.org/10.1371/journal.pone.0035890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342291/
https://www.ncbi.nlm.nih.gov/pubmed/22567116
http://dx.doi.org/10.1371/journal.pone.0035890

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