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Altered Composition of Liver Proteasome Assemblies Contributes to Enhanced Proteasome Activity in the Exceptionally Long-Lived Naked Mole-Rat
The longest-lived rodent, the naked mole-rat (Bathyergidae; Heterocephalus glaber), maintains robust health for at least 75% of its 32 year lifespan, suggesting that the decline in genomic integrity or protein homeostasis routinely observed during aging, is either attenuated or delayed in this extra...
Autores principales: | Rodriguez, Karl A., Edrey, Yael H., Osmulski, Pawel, Gaczynska, Maria, Buffenstein, Rochelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342291/ https://www.ncbi.nlm.nih.gov/pubmed/22567116 http://dx.doi.org/10.1371/journal.pone.0035890 |
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