Lrp5 Is Not Required for the Proliferative Response of Osteoblasts to Strain but Regulates Proliferation and Apoptosis in a Cell Autonomous Manner

Although Lrp5 is known to be an important contributor to the mechanisms regulating bone mass, its precise role remains unclear. The aim of this study was to establish whether mutations in Lrp5 are associated with differences in the growth and/or apoptosis of osteoblast-like cells and their prolifera...

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Detalles Bibliográficos
Autores principales: Javaheri, Behzad, Sunters, Andrew, Zaman, Gul, Suswillo, Rosemary F. L., Saxon, Leanne K., Lanyon, Lance E., Price, Joanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342322/
https://www.ncbi.nlm.nih.gov/pubmed/22567110
http://dx.doi.org/10.1371/journal.pone.0035726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342322/
https://www.ncbi.nlm.nih.gov/pubmed/22567110
http://dx.doi.org/10.1371/journal.pone.0035726

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