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The Interaction between Early Life Epilepsy and Autistic-Like Behavioral Consequences: A Role for the Mammalian Target of Rapamycin (mTOR) Pathway

Early life seizures can result in chronic epilepsy, cognitive deficits and behavioral changes such as autism, and conversely epilepsy is common in autistic children. We hypothesized that during early brain development, seizures could alter regulators of synaptic development and underlie the interact...

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Detalles Bibliográficos
Autores principales: Talos, Delia M., Sun, Hongyu, Zhou, Xiangping, Fitzgerald, Erin C., Jackson, Michele C., Klein, Peter M., Lan, Victor J., Joseph, Annelise, Jensen, Frances E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342334/
https://www.ncbi.nlm.nih.gov/pubmed/22567115
http://dx.doi.org/10.1371/journal.pone.0035885