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Immune Recognition of Gene Transfer Vectors: Focus on Adenovirus as a Paradigm

Recombinant Adenovirus (Ad) based vectors have been utilized extensively as a gene transfer platform in multiple pre-clinical and clinical applications. These applications are numerous, and inclusive of both gene therapy and vaccine based approaches to human or animal diseases. The widespread utiliz...

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Detalles Bibliográficos
Autores principales: Aldhamen, Yasser Ali, Seregin, Sergey S., Amalfitano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342374/
https://www.ncbi.nlm.nih.gov/pubmed/22566830
http://dx.doi.org/10.3389/fimmu.2011.00040