Cargando…
The Role of Coinhibitory Signaling Pathways in Transplantation and Tolerance
Negative costimulatory molecules, acting through so-called inhibitory pathways, play a crucial role in the control of T cell responses. This negative “second signal” opposes T cell receptor activation and leads to downregulation of T cell proliferation and promotes antigen specific tolerance. Much i...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Research Foundation
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342378/ https://www.ncbi.nlm.nih.gov/pubmed/22566929 http://dx.doi.org/10.3389/fimmu.2012.00047 |