Estrogenic regulation of S6K1 expression creates a positive regulatory loop in control of breast cancer cell proliferation

The 40S ribosomal S6 kinase 1 (S6K1) is an important regulator of cell growth. Expression of S6K1 is often elevated in breast cancer cells. However, the transcriptional mechanism of S6K1 overexpression is not understood. In this report, we demonstrate that estrogen activates expression of S6K1 via E...

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Detalles Bibliográficos
Autores principales: Maruani, D. Myriam, Spiegel, Tirtza N., Harris, Emily N., Shachter, Avielle S., Unger, Helen A., Herrero-González, Sandra, Holz, Marina K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342462/
https://www.ncbi.nlm.nih.gov/pubmed/22286763
http://dx.doi.org/10.1038/onc.2011.657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342462/
https://www.ncbi.nlm.nih.gov/pubmed/22286763
http://dx.doi.org/10.1038/onc.2011.657

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