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Protective Effect of Sauchinone Against Regional Myocardial Ischemia/Reperfusion Injury: Inhibition of p38 MAPK and JNK Death Signaling Pathways

Sauchinone has been known to have anti-inflammatory and antioxidant effects. We determined whether sauchinone is beneficial in regional myocardial ischemia/reperfusion (I/R) injury. Rats were subjected to 20 min occlusion of the left anterior descending coronary artery, followed by 2 hr reperfusion....

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Detalles Bibliográficos
Autores principales: Kim, Seok Jai, Jeong, Cheol Won, Bae, Hong Beom, Kwak, Sang Hyun, Son, Jong-Keun, Seo, Chang-Seob, Lee, Hyun-Jung, Lee, JongUn, Yoo, Kyung Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342554/
https://www.ncbi.nlm.nih.gov/pubmed/22563228
http://dx.doi.org/10.3346/jkms.2012.27.5.572