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Complexity of the microglial activation pathways that drive innate host responses during lethal alphavirus encephalitis in mice

Microglia express multiple TLRs (Toll-like receptors) and provide important host defence against viruses that invade the CNS (central nervous system). Although prior studies show these cells become activated during experimental alphavirus encephalitis in mice to generate cytokines and chemokines tha...

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Detalles Bibliográficos
Autores principales: Esen, Nilufer, Blakely, Pennelope K, Rainey-Barger, Emily K, Irani, David N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342594/
https://www.ncbi.nlm.nih.gov/pubmed/22471445
http://dx.doi.org/10.1042/AN20120016