Cargando…

A reporter system for translational readthrough of stop codons in human cells

Agents to induce readthrough of premature termination codons (PTCs) are useful research tools and potential therapeutics. Reporters used to detect PTC readthrough are gene-specific and thus are not suited to for general assessment of readthrough activity or in cases where PTC-inactivated genes are u...

Descripción completa

Detalles Bibliográficos
Autores principales: Halvey, Patrick J., Liebler, Daniel C., Slebos, Robbert J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342693/
https://www.ncbi.nlm.nih.gov/pubmed/22563532
http://dx.doi.org/10.1016/j.fob.2012.04.004