Synthesis and anti-HSV-1 evaluation of new 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridines

BACKGROUND: Herpes simplex virus type-1 (HSV-1) is the primary cause of facial lesions (mouth, lips, and eyes) in humans. The widespread use of acyclovir and nucleoside analogues has led to emergence of HSV strains that are resistant to these drugs. Recently, non-nucleoside anti-HSV compounds have r...

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Detalles Bibliográficos
Autores principales: Bernardino, Alice MR, Azevedo, Alexandre R, Pinheiro, Luiz CS, Borges, Júlio C, Paixão, Izabel CP, Mesquita, Milene, Souza, Thiago ML, dos Santos, Maurício S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342845/
https://www.ncbi.nlm.nih.gov/pubmed/22373524
http://dx.doi.org/10.1186/2191-2858-2-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342845/
https://www.ncbi.nlm.nih.gov/pubmed/22373524
http://dx.doi.org/10.1186/2191-2858-2-3

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