Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells

BACKGROUND: Previously assumed to be a select ligand for chemokine receptor CXCR4, chemokine CXCL12 is now known to activate both CXCR4 and CXCR7. However, very little is known about the co-expression of these receptors in cancer cells. METHODS: We used immunohistochemistry to determine the extent o...

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Detalles Bibliográficos
Autores principales: Heinrich, Eileen L, Lee, Wendy, Lu, Jianming, Lowy, Andrew M, Kim, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342892/
https://www.ncbi.nlm.nih.gov/pubmed/22472349
http://dx.doi.org/10.1186/1479-5876-10-68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342892/
https://www.ncbi.nlm.nih.gov/pubmed/22472349
http://dx.doi.org/10.1186/1479-5876-10-68

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