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Minocycline markedly reduces acute visceral nociception via inhibiting neuronal ERK phosphorylation

BACKGROUND: Minocycline prevents the development of neuropathic and inflammatory pain by inhibiting microglial activation and postsynaptic currents. But, how minocycline obviates acute visceral pain is unclear. The present study investigated whether minocycline had an any antinociceptive effect on a...

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Detalles Bibliográficos
Autores principales: Cho, Ik-Hyun, Lee, Min Jung, Jang, Minhee, Gwak, Nam Gil, Lee, Ka Yeon, Jung, Hyuk-Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342906/
https://www.ncbi.nlm.nih.gov/pubmed/22364340
http://dx.doi.org/10.1186/1744-8069-8-13