The C. elegans H3K27 Demethylase UTX-1 Is Essential for Normal Development, Independent of Its Enzymatic Activity

Epigenetic modifications influence gene expression and provide a unique mechanism for fine-tuning cellular differentiation and development in multicellular organisms. Here we report on the biological functions of UTX-1, the Caenorhabditis elegans homologue of mammalian UTX, a histone demethylase spe...

Descripción completa

Detalles Bibliográficos
Autores principales: Vandamme, Julien, Lettier, Gaëlle, Sidoli, Simone, Di Schiavi, Elia, Nørregaard Jensen, Ole, Salcini, Anna Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342935/
https://www.ncbi.nlm.nih.gov/pubmed/22570628
http://dx.doi.org/10.1371/journal.pgen.1002647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342935/
https://www.ncbi.nlm.nih.gov/pubmed/22570628
http://dx.doi.org/10.1371/journal.pgen.1002647

Ejemplares similares