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The C. elegans H3K27 Demethylase UTX-1 Is Essential for Normal Development, Independent of Its Enzymatic Activity
Epigenetic modifications influence gene expression and provide a unique mechanism for fine-tuning cellular differentiation and development in multicellular organisms. Here we report on the biological functions of UTX-1, the Caenorhabditis elegans homologue of mammalian UTX, a histone demethylase spe...
Autores principales: | Vandamme, Julien, Lettier, Gaëlle, Sidoli, Simone, Di Schiavi, Elia, Nørregaard Jensen, Ole, Salcini, Anna Elisabetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342935/ https://www.ncbi.nlm.nih.gov/pubmed/22570628 http://dx.doi.org/10.1371/journal.pgen.1002647 |
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