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YY1 Regulates Melanocyte Development and Function by Cooperating with MITF

Studies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed profound melanocyte deficiency and premature gray hair, similar to the loss of m...

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Detalles Bibliográficos
Autores principales: Li, Juying, Song, Jun S., Bell, Robert J. A., Tran, Thanh-Nga T., Haq, Rizwan, Liu, Huifei, Love, Kevin T., Langer, Robert, Anderson, Daniel G., Larue, Lionel, Fisher, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342948/
https://www.ncbi.nlm.nih.gov/pubmed/22570637
http://dx.doi.org/10.1371/journal.pgen.1002688