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LINT, a Novel dL(3)mbt-Containing Complex, Represses Malignant Brain Tumour Signature Genes

Mutations in the l(3)mbt tumour suppressor result in overproliferation of Drosophila larval brains. Recently, the derepression of different gene classes in l(3)mbt mutants was shown to be causal for transformation. However, the molecular mechanisms of dL(3)mbt-mediated gene repression are not unders...

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Detalles Bibliográficos
Autores principales: Meier, Karin, Mathieu, Eve-Lyne, Finkernagel, Florian, Reuter, L. Maximilian, Scharfe, Maren, Doehlemann, Gunther, Jarek, Michael, Brehm, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342951/
https://www.ncbi.nlm.nih.gov/pubmed/22570633
http://dx.doi.org/10.1371/journal.pgen.1002676