Cargando…

MicroRNA-277 Modulates the Neurodegeneration Caused by Fragile X Premutation rCGG Repeats

Fragile X-associated tremor/ataxia syndrome (FXTAS), a late-onset neurodegenerative disorder, has been recognized in older male fragile X premutation carriers and is uncoupled from fragile X syndrome. Using a Drosophila model of FXTAS, we previously showed that transcribed premutation repeats alone...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Huiping, Poidevin, Mickael, Li, He, Chen, Dahua, Jin, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343002/
https://www.ncbi.nlm.nih.gov/pubmed/22570635
http://dx.doi.org/10.1371/journal.pgen.1002681