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MicroRNA-277 Modulates the Neurodegeneration Caused by Fragile X Premutation rCGG Repeats
Fragile X-associated tremor/ataxia syndrome (FXTAS), a late-onset neurodegenerative disorder, has been recognized in older male fragile X premutation carriers and is uncoupled from fragile X syndrome. Using a Drosophila model of FXTAS, we previously showed that transcribed premutation repeats alone...
Autores principales: | Tan, Huiping, Poidevin, Mickael, Li, He, Chen, Dahua, Jin, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343002/ https://www.ncbi.nlm.nih.gov/pubmed/22570635 http://dx.doi.org/10.1371/journal.pgen.1002681 |
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