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Age-Dependent TLR3 Expression of the Intestinal Epithelium Contributes to Rotavirus Susceptibility
Rotavirus is a major cause of diarrhea worldwide and exhibits a pronounced small intestinal epithelial cell (IEC) tropism. Both human infants and neonatal mice are highly susceptible, whereas adult individuals remain asymptomatic and shed only low numbers of viral particles. Here we investigated age...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343008/ https://www.ncbi.nlm.nih.gov/pubmed/22570612 http://dx.doi.org/10.1371/journal.ppat.1002670 |